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Showing posts with the label research

P5–99: Greater interelectrode distance in biventricular pacing predicts response to cardiac resynchronization therapy in patients with congestive heart failure

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  Ian Weisberg MD Ian Weisberg MD , Binu Jacob MD, Alan Miller MD, Steve S. Hsu MD Background Cardiac resynchronization therapy (CRT) in heart failure patients with dyssynchrony leads to a significant improvement in quality of life; however, some of patients who receive CRT are non-responders. There is little data on intraprocedural parameters that can predict response to CRT. We have hypothesized that greater interelectrode distance between the left ventricular (LV) and right ventricular (RV) leads would result in earlier complete depolarization of the left ventricle, narrower QRS. Methods We retrospectively studied 22 patients who met criteria for biventricular (Bi-V) pacemaker or defibrillator implantation. All patients received endovascular leads. A blinded heart failure physician determined responders (n=12) and non-responders (n=10) based on improvement in New York Heart Association (NYHA) functional class. There was no baseline difference between the two groups with respect ...

Abstract 2491: Same-Day Device Reimplantation Following Cardiovascular Implantable Electronic Device Extraction for Isolated Pocket Infection

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  Dr. Ian Weisberg Abstract Objective: Limited published data show outcomes in patients with cardiovascular implantable electronic device (CIED) reimplantation on the same day that a CIED is removed due to isolated pocket infection. Methods: A retrospective, cohort study was performed in consecutive patients undergoing CIED extraction for infection from 1999–2008. We analyzed the cohort for patient and infection characteristics as well as for procedure indications, details, and outcomes. Results: Forty-nine patients [mean age 70.6 years; 44 (88%) male] of 138 (36%) infection extractions underwent same-day CIED reimplantation following successful complete extraction for an isolated pocket infection. These patients had pocket swelling, fistula, and/or erosion; blood cultures grew no organisms and no vegetations were seen with TEE. Thirty-six patients (76%) were pacemaker-dependent and 7 (14%) had CRT devices. The mean time from the most recent CIED procedure to infection was 13.8 m...

Initial experience using a radiofrequency powered transseptal needle — PubMed

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  Dr. Ian Weisberg Matthew P Smelley 1 , Dipak P Shah , Ian Weisberg , Susan S Kim , Albert C Lin , John F Beshai , Martin C Burke , Bradley P Knight Abstract Introduction: The purpose of this study was to determine the safety and efficacy of using a novel radiofrequency (RF) powered transseptal needle to perform transseptal puncture (TSP). Methods: TSP was performed in 35 consecutive patients undergoing left-sided catheter ablation (mean age = 51 years; male = 71%) using a RF powered transseptal needle (NRG, Adult Large and Standard Curve C1, 71 cm, Baylis Medical Company, Inc.). Prior TSP had been performed in 34% of patients. The transseptal apparatus was positioned with the tip of the dilator engaged in the fossa ovalis. RF energy was delivered to the tip of the transseptal needle using a proprietary RF generator at 10 W for 2 seconds as gentle pressure was applied to the needle. Results: In 5 of the 41 TSPs, the needle crossed into the left atrium before RF energy was deliver...

Late Potential at the High Ventricular Septal Level in a patient with Brugada: Possible mechanisms and Clinical implications

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  Dr. Ian Weisberg - Late Potential at the High Ventricular Septal Level in a patient with Brugada: Possible mechanisms and Clinical implications Case report A 34-year-old Mexican immigrant was referred for symptomatic paroxysmal atrial fibrillation. A baseline electrocardiogram (ECG) in sinus rhythm showed type 1 Brugada pattern with right bundle branch block and negative T waves as well as ST-segment elevation in V1-V3. The patient had no prior history of ventricular arrhythmia, syncope, or cardiac arrest. However, a positive family history of sudden cardiac death (brother died at age 20) prompted referral to our service for further risk Discussion Ventricular late potentials and wide and fractionated electrograms, which reflect delayed and fragmented ventricular conduction, have been reported in both the epicardium 1and endocardium 2of patients with Brugada syndrome (BS). Marked regional endocardial conduction delay and heterogeneities in repolarization exist in these pati...